...in my boxers...
There's the obvious one, war, the countries involved, and it's effect on worldwide economics and sociological structice (is that the right phrase?)...
or, perhaps, the economy; it might be hard, unless you chose a particular country. The US of A, as you know, ain't doing so well.
Cloning, and it's ethical and medical implications, I think is a very good subject to go all out on.
The fallout of the Eleventh, a smaller, but still important topic.
The epidemic of 2002 which consisted of 'rappers' featuring a feather-voiced female singer. Gag me; please, too much.
If I think of anymore, I'll be back.
"A life unexamined is not worth living."